In previous work, I have looked in detail at the capacity and the limits of the linguistics model as applied to gene expression. The recent use of a primitive applied linguistic model in Apple's SIRI system allows further analysis. In particular, the failings of this system resemble those of the HGP; the model used also helps point out the shortcomings of the concept of the "gene". This is particularly urgent as we are entering an era of applied biology in the (...) absence of theory, and indeed an era with a near-epidemic of retracted papers. There are a few workarounds proposed. One is to add to the nascent field of biosemiotics a more explicit concern with syntax. At the time of writing, Apple is being sued for false advertising of its iphone 4s, with the associated claim that apple had solved many of the problems of natural language processing by computer . The system was bought by Apple from a company called SIRI, and in turn was based on the notion, trumpeted by the prior art in a company called Dejima, that nlpbc could be done by keywords alone. Yet the hype resembles nothing so much as the misrepresentation of the Human Genome Project fed to the media in the glory days at the beginning of this millennium, and it says a lot for the status of scientists in society that they have avoided Apple's fate. In this paper, a short review of several current themes in theoretical and applied biology is first proposed. Then the tensions implicit in the notion that the "gene" is simultaneously to be identified as a unit of inheritance and spatially located over spatially well-defined nucleotides is explored and the notion is found to be incoherent. An expanded notion of inheritance is proposed in the context of a focus on inheritance as necessarily involving species, population and organism over time. While it is premature to talk about a paradigm shift, it is certainly arguable that biology urgently needs a sophisticated theory of how symbols work substantially more sophisticated than that implicit in the HGP; Biosemiotics affords a framework in which this might be tried. Indeed, as this paper concludes, there may yet be room for a "Bionoetics", a perspective in which biological explanation can be extended to include cognition in all its forms. Finally, a working sketch of a modeling environment written in LISP, one that shows promise in reflecting the complexities discussed in the paper, is included. Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}. (shrink)

ECOG data obtained from a patient under conditions of resting brain, sleep and epileptic seizure were analyzed. Contrary to some theorists, the seizure state was found to be informationally the most complex of the three states. Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}.

Abstract -/- This paper has three contrasting sections. The first starts with a description of the academic context that has led researchers like Stewart Kauffmann to introduce "God" into respectable discourse. It then goes on to juxtapose his schema with similar others that his work does not reference. It is proposed that, since humanity is the cutting edge-for good and evil-of emanation/revolution, it is human development that we must focus on. This, in turn cannot properly be discussed without reference to (...) first person descriptions and their contrast with third person descriptions. Likewise the role of those contrasting accounts within and outside the academy, which is currently under threat, must be referred to. -/- -/- Accordingly, the second section begins with the delineation of subjectivity suggested by current neuroscience. It is argued that the cluster sampling of EEG will yield significantly more meaningful results than other competing methods. -/- This paper makes the admittedly radical contention that it may be intellectually responsible to engage in forms of thought and practice that engage the whole of life in a manner heretofore addressed by “religions”. Such forms of life cannot responsibly emerge from an insight into the nature of physical reality, which is the province of the academy. Rather, these forms emerge from consideration of the human psychophysical unity as it engages with a succession of different contexts and attempts to reflect on and refine its responses to them. -/- The nature of the academy early in the 21st century is a confounding factor. The corporate pressure to attenuate academic freedom is real, as is the fact that academic freedom in liberal democracies would immediately migrate to other, initially unfunded structures in civil society with the internet offering myriad opportunities for dissemination and immediate critique of ideas. Orthogonal to this is the attempt to specify and refine one's psychological life, the bane of academic psychology from 19th century German research onwards. It is argued that academic psychology has an asymptote at this point; better to distinguish between the “academy' and the “real world” in a way that best does justice to both, and allows the layperson participate in a genuine attempt to seek knowledge by providing him with a veridical cosmology and psychology, than risk a new absurdity rivaling ontological behaviourism. Many salient facts about human psychology can be discovered by oneself in the “real world”, if only because the imperatives there will always be more compelling, try as we might. -/- -/- Finally, a synthetic narrative is proposed, one in which the evolutionary ethos of the first section is interrelated with the signs of the second section. This final section may yet be read independently of its predecessors. Kauffman’s imperative “reinventing the sacred” indicates something is awry in our conceptual and political systems; it is argued that historically authentic religious movements have preserved something they considered divine, and done so on the margins of society. In fact, this marginalization may be the essence of the religious impulse. (shrink)

This is the introduction to the special edition on Foundations of Mind: Cognition and Consciousness and the introduction to the conference at UC University at Berkeley on which the edition is based.

Use of symbols, the key to the biosemiotics field as to many others, required bigger brains which implied a promissory note for greater energy consumption; symbols are obviously expensive. A score years before the current estimate of 18–20% for the human brain’s metabolic demand on the organism, it was known that neural tissue is metabolically dear. This paper first discusses two evolutionary responses to this demand, on both of which there is some consensus. The first, assigning care of altricial infants (...) with burgeoning brains (and in human infants the metabolic demand peaks at 65% of the total) to “allomothers” is not unique to humans. The second, using relatively small neurons as primates do, risks misfires past a certain minimal value. Moreover, in apparent paradox, there is an increasing consensus that large “Von Economo” neurons are critical for communication. This paper’s main contribution is the discussion of two further evolutionary tricks. The first is the use of self-similarity in the cortex, both in structure and process, to allow the cortex readily—and in energetic terms, parsimoniously—to shift between states in a high-dimensional space. This leads to discussion of the kind of formalism appropriate to model these shifts, a formalism which—it is tentatively suggested—may do double duty for the modeling of symbolic thought. The second trick is the superimposition on the background “white noise” of neural firing of EEG-detected waves like gamma. The paper describes a method, using the Hilbert transform, of calculating the dips in energy consumption as the brain is transitioned by gamma waves. It is hypothesized that consciousness may be a spandrel, the incidental result of a neurodynamic imperative that the brain enter a maximally sensitive (in sensory terms) “zero power” state a few times a second. If that is the case, then there are obvious benefits for health in meditation, which can be viewed as a state of consciousness extended over time by limiting afferent stimuli. (shrink)

This is the introduction to the Special Issue: Foundations of Mind II: A Dialogue of World-Views.

Over the past half-century, the Freeman laboratory has accumulated a large volume of data and a correspondingly extensive interpretive framework centered around an alternative perspective on brain function, that of dynamical systems. The purpose of this paper is first briefly to summarise this work, and bring it into dialogue with other perspectives. The contents of consciousness are seen as an inevitably sparse sample of events in the perception–action cycle. The paper proceeds to an attempt to elucidate the contents of this (...) sparse sample. A critical concept is that of selfhood, and how it presents itself phenomenologically. It is argued that our experience of selfhood is an artifact of the necessity of preservation of subject/object relations. As this part of metaphysics has been badly misunderstood, we scrutinise it at some length in quantum mechanics, biology, and cognition. It is argued that Pattee's approach, while valuable, tends to premature closure on these issues. The paper then proceeds to outline a view on how selfhood is best considered wrt the immune response. This is interrelated with phenomenology, and some data are adduced to support this central hypothesis. Finally, consequences for the social sciences in general are hinted at. (shrink)

This is a description of the aims, agenda and organization of a conference, organized by Foundations of Mind and hosted by the CIIS Centre for Consciousness Studies that took place on 31st January, 2017. Teh proceedings of this conference are published in this special edition. The topic was 'Quantum Mechanics Meets Neurodynamics: An Emerging 21st Century Science of Consciousness'. This the fourth Foundations fo Mind conference. The proceedings of the other three conferences have also been published in Cosmos and History.

Introduction to the third special edition on the Foundations of Mind: Foundations of Mind: Hommage to Walter Freeman III.

For a variety of reasons, consciousness and selfhood are beginning once again to be intensively studied in a scientific frame of reference. The notions of each which are emerging are extremely varied: in the case of selfhood, the lack of an adequate vocabulary to capture various aspects of subjectivity has led to deep confusion. The task of the first part of this article is to clear up this terminological confusion, while salvaging whatever is valuable from the contemporary discussion. The more (...) important task of the second part is to discuss the moral issues inevitably involved in any treatment, scientific or otherwise, of the modern identity. (shrink)

This paper focuses on the disparate phenomena we psychologize as “selfhood”. A central argument is that, far from being a deus ex machina as required in the Cartesian schema, our felt experience of self is above all a consequence of data compression. In coming to this conclusion, it considers in turn the Cartesian epiphany, other traditional and contemporary perspectives, and a half-century’s empirical work in the Freeman lab on neurodynamics. We introduce the concept of consciousness qua process as a force.

Review Artcile of an anthology of writings inspired by Patrick Suppes, "Foundations and Methods from Mathematics to Neuroscience" examined in the context of Suppes' life and philosophical development.

Review of "Reclaiming Enchantment: Humanity In A Creative Universe" by Stuart Kauffman NY: OUP, 2016.

This commentary shall focus on the central claim made in Lynch et al.’s paper “Promoting Ethical Payment in Human Infection Challenge Studies.” According to their paper, there is a threefold...

The authors provide this addendum to the following article to provide corrections to the results reported and further explanation of the structural equation modeling techniques utilized: Sean T. Hannah, Bruce J. Avolio, and Fred O. Walumbwa, “The Relationships between Authentic Leadership, Moral Courage, and Ethical and Pro-Social Behaviors,” Business Ethics Quarterly 21:4 : 555–78.

We present nine facets for the analysis of the past and future evolution of AI. Each facet has also a set of edges that can summarise different trends and contours in AI. With them, we first conduct a quantitative analysis using the information from two decades of AAAI/IJCAI conferences and around 50 years of documents from AI topics, an official database from the AAAI, illustrated by several plots. We then perform a qualitative analysis using the facets and edges, locating AI (...) systems in the intelligence landscape and the discipline as a whole. This analytical framework provides a more structured and systematic way of looking at the shape and boundaries of AI. (shrink)

ABSTRACT:Organizations constitute morally-complex environments, requiring organization members to possess levels of moral courage sufficient to promote their ethical action, while refraining from unethical actions when faced with temptations or pressures. Using a sample drawn from a military context, we explored the antecedents and consequences of moral courage. Results from this four-month field study demonstrated that authentic leadership was positively related to followers’ displays of moral courage. Further, followers’ moral courage fully mediated the effects of authentic leadership on followers’ ethical and (...) pro-social behaviors. Theoretical and practical implications for further integrating the work on moral courage, authentic leadership and ethics are discussed. (shrink)

This paper presents a new model for how to jointly analyze the ethical and evidentiary dimensions of environmental science cases, with an eye toward making science more participatory and publically...

A diagonal version of the strong reflection principle is introduced, along with fragments of this principle associated with arbitrary forcing classes. The relationships between the resulting principles and related principles, such as the corresponding forcing axioms and the corresponding fragments of the strong reflection principle, are analyzed, and consequences are presented. Some of these consequences are “exact” versions of diagonal stationary reflection principles of sets of ordinals. We also separate some of these diagonal strong reflection principles from related axioms.

Bioethics: 50 Puzzles, Problems, and Thought Experiments collects 50 cases—both real and imaginary—that have been, or should be, of special interest and importance to philosophical bioethics. Cases are collected together under topical headings in a natural order for an introductory course in bioethics. Each case is described in a few pages, which includes bioethical context, a concise narrative of the case itself, and a discussion of its importance, both for broader philosophical issues and for practical problems in clinical ethics and (...) health policy. Each entry also contains a brief, annotated, list of suggested readings. In addition to the classic cases in bioethics, the book contains discussion of cases that involve several emerging bioethical issues: especially, issues around disability, social justice, and the practice of medicine in a diverse and globalized world. (shrink)

How was the world generated and how does matter continue to be ordered so that the world can continue functioning? Questions like these have existed as long as humanity has been capable of rational thought. In antiquity, Plato's Timaeus introduced the concept of the Demiurge, or Craftsman-god, to answer them. This lucid and wide-ranging book argues that the concept of the Demiurge was highly influential on the many discussions operating in Middle Platonist, Gnostic, Hermetic and Christian contexts in the first (...) three centuries AD. It explores key metaphysical problems such as the origin of evil, the relationship between matter and the First Principle and the deployment of ever-increasing numbers of secondary deities to insulate the First Principle from the sensible world. It also focuses on the decreasing importance of demiurgy in Neoplatonism, with its postulation of procession and return. (shrink)

Shors & Matzel's target article is a thought-provoking attempt to reconceptualise long-term potentiation as an attentional or arousal mechanism rather than a memory storage mechanism. This is incompatible with the facts of the neurobiology of attention and of the behavioural neurophysiological properties of hippocampal neurons.

Although body alterations, including body art, sexual alteration, technological enhancements, and cosmetic surgery, usually are evaluated separately, they also can be approached by identifying common cultural trends. Because a person’s conception of identity lies at the core of many body alterations, any change to the body must pursue sincere authenticity, the virtue that fulfills one’s true identity.

Examines the pleasures, perils, and promises of professing one's sexual identity.